DNA-PK-mediated phosphorylation of STAT6 establishes a non-canonical type 2 immunity axis to prevent macrophage senescence

Nature.com

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Summary

STAT6 mitigates cellular aging and senescence by regulating the expression of DNA repair genes. However, the upstream signals driving the activation of this non-canonical STAT6 function have not been identified. Here, the authors identify DNA-PK as a key kina

Source: Nature.com

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