Three in 5 cases of most challenging cancer to treat could be prevented, scientists say how to slash your risk today

The Sun

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THE number of cases of the “most challenging cancer to treat” are set to double by 2050, academics have said.But three in five cases are due to preven

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Q1: What are the primary prevention strategies for skin cancer, one of the most common cancers globally?

A1: Primary prevention strategies for skin cancer include reducing exposure to ultraviolet (UV) radiation from the sun and avoiding tanning beds. Sunscreen use is effective in preventing melanoma and squamous-cell skin cancer. Education about the risks of UV exposure and regular skin checks are also recommended to catch early signs of skin cancer.

Q2: How significant is the role of UV radiation in the development of skin cancer?

A2: UV radiation plays a major role in skin cancer development, responsible for more than 90% of cases. It contributes to all three main types of skin cancer: basal-cell carcinoma, squamous-cell carcinoma, and melanoma. The risk is particularly high with childhood exposure for melanomas and basal-cell cancers.

Q3: What are the challenges in treating skin cancer, and how do treatment strategies vary?

A3: The challenges in treating skin cancer include its potential to spread and the need for early detection. Treatment strategies vary: nonmelanoma skin cancers are often curable with surgical removal, while melanoma may require a combination of surgery, chemotherapy, radiation, and targeted therapy. Palliative care may be necessary for advanced cases.

Q4: What does the latest research suggest about the use of machine learning in cancer treatment strategies?

A4: Recent research indicates that machine learning can improve the estimation of optimal adaptive treatment strategies (ATSs) using dynamic weighted ordinary least squares (dWOLS). Machine learning methods have shown better performance than traditional logistic regression models in terms of bias and variance, particularly in complex scenarios.

Q5: How does preventive healthcare contribute to reducing cancer incidence?

A5: Preventive healthcare aims to reduce disease incidence by addressing factors such as environment, genetics, and lifestyle before individuals are affected. It involves regular screenings, lifestyle modifications, and vaccination to lower cancer risk, thereby decreasing the overall incidence and improving population health.

Q6: What are the latest advancements in identifying and managing skin cancer risk factors?

A6: Advancements include improved public awareness of UV risks, development of UV-protective clothing, and enhanced imaging technologies for early detection. Genetic research is also underway to better understand individual susceptibility and tailor preventive measures accordingly.

Q7: What are the global trends in skin cancer prevalence, and which populations are most affected?

A7: Skin cancer prevalence has increased globally, with nonmelanoma skin cancer being the most common. Populations with lighter skin, particularly in Australia, New Zealand, and South Africa, face higher melanoma rates due to UV exposure. Efforts focus on reducing incidence through public health campaigns and protective measures.

References:

  • Skin cancer
  • Preventive healthcare
  • Using Machine Learning to Improve Control for Confounding in the Dynamic Weighted Ordinary Least Squares Estimator of Optimal Adaptive Treatment Strategies