Summary
The family of a woman, who was aged 110, have paid tribute to her. Theresa Ryan was described by her family as a “cheeky and mischievous” lady who loved to laugh. Grandson Ross Symons said Mrs Ryan was 110 years old and 319 days old, nearly 111 years old, when she died on 17 April.
Source: BBC

AI News Q&A (Free Content)
Q1: What trends have been observed in the global population of centenarians, and how is this expected to change in the future?
A1: The global population of centenarians has been increasing significantly. In 2012, there were approximately 316,600 centenarians worldwide, and this number rose to 573,000 by 2020. The United Nations has projected that the number of centenarians will continue to grow, with countries like Japan expecting as many as 1 million by 2050.
Q2: What are some of the factors contributing to the longevity of individuals who live beyond 100 years?
A2: Research indicates that factors contributing to longevity include genetics, lifestyle choices, and environmental influences. Studies on centenarians show that a balanced diet, regular physical activity, and a supportive social environment are common among those who live to be 100 years or older.
Q3: How does the concept of structural complexity relate to the potential longevity of organisms, according to recent studies?
A3: Recent studies suggest that the potential longevity of an organism is closely linked to its structural complexity. This complexity determines both the development time and maintenance time of an organism. The degree of damage exposure and the environment play significant roles in the actual lifespan of an organism, despite having the same potential for longevity.
Q4: What are some health benefits of dietary methionine restriction in old age as per recent research?
A4: Recent research indicates that dietary methionine restriction can promote healthy aging when started later in life. This restriction has been found to improve several health markers and reduce health risks associated with aging, although effects can vary based on sex.
Q5: What role do longevity derivatives play in managing systematic mortality risk in life annuities?
A5: Longevity derivatives, such as index-based longevity swaps and caps, are crucial for managing systematic mortality risk in life annuities. They provide financial protection against unexpected increases in life expectancy, offering downside protection and helping insurers manage longevity risk more effectively.
Q6: What insights have been gained from studies on the bending of the shape parameter and mortality deceleration in longevity research?
A6: Studies have shown that the bending of the shape parameter in survival curves is associated with mortality deceleration, which can indicate a mathematical limit of longevity. This phenomenon suggests that as people age, the rate of mortality increase slows down, providing insights into the dynamics of aging and mortality.
Q7: How does the GJA1/SIRT1 pathway contribute to combating oocyte aging, as explored in recent research?
A7: The GJA1/SIRT1 pathway plays a pivotal role in combating oocyte aging by maintaining mitochondrial function and cellular homeostasis. Recent research has shown that targeting this pathway with Echinacoside can restore mitochondrial dynamics, reduce oxidative stress, and enhance genomic stability, making it a promising candidate for addressing reproductive challenges related to aging.
References:
- Centenarian - https://en.wikipedia.org/wiki/Centenarian
- Longevity - https://en.wikipedia.org/wiki/Longevity
- Revitalising Aging Oocytes: Echinacoside Restores Mitochondrial Function and Cellular Homeostasis Through Targeting GJA1/SIRT1 Pathway - Cell Proliferation